Advanced Imaging in the Current Era of Acute Reperfusion Therapies

Reperfusion of the ischemic brain parenchyma with intravenous thrombolysis and/or mechanical thrombectomy is cornerstone acute stroke treatment. A paradigm shift from “time brain” to a more precision medicine approach now called “imaging brain”, has taken place during last decade. This transformation been fueled by progress in neuroimaging. Advanced Neuroimaging incorporates perfusion imaging order depict real-time cerebral disturbances and provide maps penumbra core that will inform individualized clinical decisions. Advance neuroimaging fundamental role triaging patients receive reperfusion treatments beyond conventional time windows 4.5 hours for 6 thrombectomy. We narrative review all pivotal observational studies randomized-controlled trials supported use advance neuroimaging, as well technical issues pitfalls may be useful its implementation routine practice.